Professor Chang, Hsueh-Wei
Ph.D. Department of Life Science, National Tsing-Hua University
Postdoctorial researcher, Johns Hopkins University School of Medicine, USA
Biochemisrty, Biology, Molecular Biology, Bioinformatics, Genomics, Special topic in cell biology, Special topic in Bioinformatics
Anticancer drug screening from natural product, SNP, Genomics, Cancer genetics, Bioinformatics, molecular avian gender identification.
[Technical Editor] 1. Theriogenology Insight -International journal of Reproduction in all Animals
[Guest editor for special issue] 1. The World Scientific Journal- Biochemistry domain
[Editorial Board] 1. Recent Patents on Biomarkers; 2. The Open Systems Biology Journal; 3. The Open Access Journal of Science and Technology.
1. Establishment of DNA damage or repair analytic platform for natural and synthetic drugs
Coperating with Institute of Natural Products to screen drugs with anti-cancer and antioxidative stress proterties.
2. Developing and renew of bioinformatics tool
Cooperation with computational experts to improve the bioinformatics tool related to SNP genotyping, SNP-SNP interaction, feature selection
3. SNP genotyping, haplotyping and association study
DNA from any source, e.g., hair shafts, blood, or buccal, urine and saliva is suitable for analysis. Under properly sampling for certain diseases, the risk factor for specific SNP associated with diseases is estimated. Mining haplotype-based SNP candidates is concerned. Recently topics include osteoporosis, bladder and oral cancers.
4. Molecular gender identification of birds
High throughput analysis for gender identification of birds.
5. Development of noninvasive DNA extraction from patients.
Currently, we are successfully performed PCR from urine and saliva extracted DNA.